Peixe Rosa — Life Sciences & Translational Medicine

NANOSENSING

NanoPlasmonic Cardiovascular Diagnostics

Precision sensing technology for point-of-care cardiovascular assessment and the development of a broader diagnostic platform.

NANOSENSING brings together nanomaterials, optical spectroscopy and biomarker measurement in a technology platform originally developed to support rapid cardiac assessment.

Its initial application focuses on cardiac troponin I, an established biomarker of myocardial injury, through a proposed point-of-care diagnostic instrument and treated disposable microcuvettes.

Of Joseph PB&T presents NANOSENSING as an opportunity to organize established scientific work into an internationally structured diagnostics enterprise, advancing independent validation, product engineering, regulatory preparation and global commercialization.

NANOSENSING — US$6 Million Co-Investment Opportunity

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Timely Information at the Point of Care

Cardiovascular emergencies place considerable demands on clinical decision-making. Cardiac troponin measurements form an important part of evaluating suspected myocardial injury and myocardial infarction.

NANOSENSING's original technology program addresses the opportunity for compact diagnostic instrumentation capable of measuring cardiac biomarkers closer to the point of care.

The commercial objective is to advance a practical diagnostic system for appropriately authorized clinical environments, supporting timely access to biomarker information within established medical assessment pathways.

Troponin results must be interpreted alongside clinical presentation, electrocardiography and other relevant diagnostic information. The technology is not presented as a standalone determination of myocardial infarction.

Nanoplasmonic Measurement. Applied Diagnostics.

The scientific foundation is the NanoPlasmonic Technology Platform, or NPTP, developed around modified metallic nanoparticles and optical spectroscopy.

The historical technical materials describe the use of plasmonic optical responses to detect and quantify selected biomarkers, including cardiac troponin I.

The proposed diagnostic configuration combines:

A point-of-care instrument

An optical measurement device designed around the platform's spectroscopy-based sensing method.

Treated disposable microcuvettes

Single-use test components incorporating the materials and procedures necessary for biomarker measurement.

A reusable technology foundation

A nanoplasmonic sensing approach with potential applicability to additional biomarkers and diagnostic indications, subject to separate technical and clinical validation.

This architecture supports both a defined first product and a longer-term platform-development strategy.

A Scientific Foundation Established Through Prior Development

The NANOSENSING program is supported by historical scientific and engineering work undertaken by researchers associated with Recife, Brazil.

The source materials describe development of the NPTP technology, prototype instrumentation, patent-related work and historical clinical-testing activity associated with the cardiac troponin application.

These materials provide an identifiable technical foundation for renewed product development and independent assessment.

The next enterprise phase is designed to establish the current technical position through documented review of the underlying research, intellectual property, prototype condition, analytical performance and clinical evidence.

Historical performance figures, testing timelines and regulatory assertions will be independently verified before being used as current product specifications or commercialization claims.

Three Complementary Sources of Enterprise Value

NANOSENSING's commercial proposition combines diagnostic hardware, recurring test consumables and platform intellectual property.

Diagnostic instrumentation

Development and commercialization of point-of-care measurement systems for eligible healthcare environments, directly or through established industry partners.

Recurring consumables

Treated single-use microcuvettes associated with diagnostic testing. A successfully commercialized installed instrument base may create recurring demand for validated, approved consumables.

Technology licensing and partnerships

Licensing, co-development and strategic commercialization arrangements with diagnostic manufacturers and other qualified industry participants.

The platform may support additional biomarker applications where the underlying science, intellectual-property rights, clinical requirements and commercial case justify further development.

No current sales, customer contracts, product pricing or recurring revenues should be asserted without verified supporting records.

From Scientific Development to an Independent Global Enterprise

Of Joseph PB&T's investment strategy is to organize NANOSENSING as an independently governed, internationally investable diagnostics enterprise.

The contemplated structure places a Cayman-incorporated parent company at the center of enterprise governance, international capitalization and long-term public-market readiness.

Appropriate operating and development arrangements may include Brazil, the United States and other relevant jurisdictions.

The enterprise structure will be determined with reference to the existing corporate and intellectual-property position.

The enterprise capitalization will be structured around the verified intellectual-property position, including the rights associated with Nanosensing Technologies, Inc. and the historical participation of Of Joseph PB&T Foundation. The appropriate ownership, licensing and commercialization arrangements will be established through definitive agreements with the relevant rights holders.

Of Joseph PB&T's originating and structuring role must remain distinct from the ownership, obligations and governance of the eventual operating enterprise.

Scientific Continuity. Institutional Execution.

NANOSENSING sits within the investment activities associated with Peixe Rosa, Of Joseph PB&T's life-sciences and translational-medicine ecosystem.

This relationship provides a framework for connecting scientific development with relevant research institutions, clinical expertise, translational capabilities and enterprise execution in Brazil.

Recife and the wider Pernambuco research environment offer a practical setting for technical assessment, qualified talent recruitment and institutional collaboration.

Specific laboratory, hospital and research activities will proceed under the relevant agreements, authorizations and technical protocols.

The objective is to combine the advantages of the Brazilian scientific environment with international standards of product development, governance and commercialization.

US$6 MILLION

Initial Co-Investment Capitalization

Of Joseph PB&T is presenting an initial co-investment opportunity of US$6 million to support the establishment and advancement of NANOSENSING as an independent international diagnostics enterprise.

The capitalization is intended to support the following development priorities:

  • Corporate organization, governance and intellectual-property arrangements.
  • Independent assessment of the underlying technology and existing evidence.
  • Diagnostic instrument and consumables engineering.
  • Analytical and clinical validation planning and execution.
  • Regulatory strategy and quality-management development.
  • Manufacturing feasibility and supply-chain preparation.
  • Recruitment of experienced enterprise and technical leadership.
  • Commercial partner engagement and international market preparation.

The deployment sequence will follow approved operating budgets and measurable development milestones.

This capitalization represents the initial enterprise financing target, not a representation that all regulatory authorizations, manufacturing operations or global commercial launches can be completed within that amount.

An Enterprise Built Around Defined Milestones

Technical consolidation

Review the technology, existing prototypes, research records, intellectual-property position and product-development requirements.

Independent verification

Establish reproducible analytical performance, clinical validation requirements and a documented product specification.

Product and regulatory readiness

Advance instrument engineering, treated microcuvettes, quality systems, manufacturing processes and the applicable regulatory submission strategy.

Commercial partnerships

Engage diagnostic manufacturers, healthcare technology companies, distribution partners and potential licensees under appropriate confidentiality and diligence arrangements.

International enterprise development

Build the management, governance, reporting and financial foundations appropriate for subsequent institutional capitalization and potential public-market participation.

Any eventual public listing remains dependent on applicable requirements, enterprise development and market conditions.

A Diagnostic Application. A Broader Technology Platform.

NANOSENSING combines a recognizable clinical application with a technology architecture capable of supporting multiple commercial pathways.

Its investment proposition rests on five foundations:

Scientific heritage

prior development of an identifiable nanoplasmonic sensing platform.

Clinical relevance

an initial focus on cardiac troponin I measurement.

Commercial structure

instrumentation, recurring consumables and potential technology licensing.

International enterprise formation

independent governance and Cayman-based capitalization architecture.

Platform optionality

the potential to pursue additional validated biomarkers and applications through future partnerships and development programs.

The commercial opportunity is to convert prior scientific development into a disciplined, internationally structured diagnostics business.

Participate in the Development of NANOSENSING

Of Joseph PB&T welcomes inquiries from qualified co-investors, strategic industry participants and commercial partners interested in the capitalization and development of NANOSENSING.

Detailed participation terms are provided privately to qualified investors.

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